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Cotton Fleece Fabric: What It Is and How to Use It Cotton fleece is a knitted cotton fabric that has been brushed on one or both sides to raise a soft, plush pile, giving it a smooth outer face and a fuzzy, insulating inner surface. It’s the fabric behind your favorite hoodie, and understanding it helps you buy smarter and sew better. Quick facts: Most common uses: hoodies, sweatshirts, sweatpants, children’s wear, and casual blankets Typical fiber content: 100% cotton or cotton-polyester blends in ratios like 80/20 or 60/40 Key trade-off: breathable and skin-friendly, but slower to dry than …